Author: Michael P McRae; Glennon W Simmons; Nicolaos J Christodoulides; Zhibing Lu; Stella K Kang; David Fenyo; Timothy Alcorn; Isaac P Dapkins; Iman Sharif; Deniz Vurmaz; Sayli S Modak; Kritika Srinivasan; Shruti Warhadpande; Ravi Shrivastav; John T McDevitt
Title: Clinical Decision Support Tool and Rapid Point-of-Care Platform for Determining Disease Severity in Patients with COVID-19 Document date: 2020_4_22
ID: h4lsvgxo_3
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04. 16.20068411 doi: medRxiv preprint proBNP. Patients with cardiac injury also more frequently required noninvasive mechanical ventilation (46.3% vs. 3.9%) or invasive mechanical ventilation (22.0% vs. 4 .2%) and experienced higher rates of complications such as ARDS (58.5% vs. 14.7%) compared to patients without cardiac injury. Ultimately,.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04. 16.20068411 doi: medRxiv preprint proBNP. Patients with cardiac injury also more frequently required noninvasive mechanical ventilation (46.3% vs. 3.9%) or invasive mechanical ventilation (22.0% vs. 4 .2%) and experienced higher rates of complications such as ARDS (58.5% vs. 14.7%) compared to patients without cardiac injury. Ultimately, patients with cardiac injury had higher mortality than those without it (51.2% vs. 4.5%). Given such data, others have recommended elevating treatment priority and aggressiveness for patients with underlying cardiovascular disease and evidence of cardiac injury. 14 This growing body of clinical evidence related to COVID-19 disease severity suggests that biomarkers can play a dominant role in a scoring system to identify COVID-19 patients with increased risk of severe disease and mortality.
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