False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

Li, Dasheng; Wang, Dawei; Dong, Jianping; Wang, Nana; Huang, He; Xu, Haiwang; Xia, Chen

Furthermore, we observed conflicting laboratory examination results in these two patients. Patient in Case 2 was infected only by SARS-CoV-2 and presented decreased lymphocytes and elevated C-reactive protein, consistent with the typical tendency found in the COVID-19 cohort. In contrast, the patient in Case 1 was coinfected with influenza A and presented with increased lymphocytes and elevated C-reactive protein. The difference in laboratory examination results could be a potential indicator of a different infection status, including SARS-CoV-2 infection alone or coinfection with other viruses, which, however, should be further validated with more cases.