Author: Liu, Chunxi; Liu, Tingxian; Yu, Xiaoyue; Gu, Yizhu
Title: A preliminary study on the interaction between Asn-Gly-Arg (NGR)-modified multifunctional nanoparticles and vascular epithelial cells Document date: 2017_4_1
ID: xio0g203_56
Snippet: In our previous studies 34 , TPIC has been developed and extensively characterized. The average particle size and zeta potential of TPIC were 199.879.2 nm and 4.39070.83 mV, respectively. TPIC was shown to be a promising carrier for the co-delivery of DNA and DOX leading to the efficiency of gene transfection and anti-tumor activity in vitro. As an extension of the intracellular study of TPIC for drug/gene co-delivery, the aim of the present stud.....
Document: In our previous studies 34 , TPIC has been developed and extensively characterized. The average particle size and zeta potential of TPIC were 199.879.2 nm and 4.39070.83 mV, respectively. TPIC was shown to be a promising carrier for the co-delivery of DNA and DOX leading to the efficiency of gene transfection and anti-tumor activity in vitro. As an extension of the intracellular study of TPIC for drug/gene co-delivery, the aim of the present study was to determine how NGR-functionalized TPIC interacts with targeted cells and promotes intracellular delivery process.
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