Selected article for: "bacterial load and overall bacterial load"
Author: Carter, Chris J.
Title: Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s Disease
  • Document date: 2017_9_28
    • ID: tmpidjrp_4
    Snippet: Preliminary microbiome studies using unbiased next-generation sequencing have also identified many fungi in AD brains (Alternaria, Botrytis, Candida, Cladosporium, and Malassezia) species [44] . A pilot next-generation sequencing study has also identified several bacterial species in both control and AD brains with an overall higher bacterial load in AD, with a relatively higher proportion of Actinobacteria, and notably Propionibacterium acnes [4.....
    Document: Preliminary microbiome studies using unbiased next-generation sequencing have also identified many fungi in AD brains (Alternaria, Botrytis, Candida, Cladosporium, and Malassezia) species [44] . A pilot next-generation sequencing study has also identified several bacterial species in both control and AD brains with an overall higher bacterial load in AD, with a relatively higher proportion of Actinobacteria, and notably Propionibacterium acnes [45] . Evidently, further microbiome studies in blood and brain are warranted for all classes of pathogens and independent confirmation across laboratories is important for individual species.

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