Selected article for: "breast cancer and cancer disease"

Author: Maslow, Joel
Title: GeneOne Life Science
  • Document date: 2018_10_26
  • ID: w7hf3kji_9
    Snippet: DNA-based therapeutics in pre-clinical development include plasmid DNA-expressed Factor VIII as a prophylactic treatment for hemophilia A, Plasmid DNA-expressed monoclonal antibody for hepatitis B immunologlobulin, Plasmid DNA expressed sc4D5-VEGF-Trap for multiple oncologic targets, and plasmid DNA expressed anti-Her2 monoclonal antibody. We have shown that the plasmid DNA -expressed anti-Her2 antibody is equally or more effective in treating He.....
    Document: DNA-based therapeutics in pre-clinical development include plasmid DNA-expressed Factor VIII as a prophylactic treatment for hemophilia A, Plasmid DNA-expressed monoclonal antibody for hepatitis B immunologlobulin, Plasmid DNA expressed sc4D5-VEGF-Trap for multiple oncologic targets, and plasmid DNA expressed anti-Her2 monoclonal antibody. We have shown that the plasmid DNA -expressed anti-Her2 antibody is equally or more effective in treating Her2 positive breast cancer in a xenograft mouse model of disease (Kim et al., Cancer Gene Therapy 2016; 23(10) 341–7).

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