Author: Carter, Chris J.
Title: Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s Disease Document date: 2017_9_28
ID: tmpidjrp_69
Snippet: Nevertheless, pathogens have to enter the brain, via the BBB or other routes, to evoke such changes and the old age of AD patients suggests that age must be a major determinant of such effects. The effects of aging in relation to the BBB and the immune system and to routes of pathogen entry are discussed below, together with other environmental risk factors that affect BBB integrity......
Document: Nevertheless, pathogens have to enter the brain, via the BBB or other routes, to evoke such changes and the old age of AD patients suggests that age must be a major determinant of such effects. The effects of aging in relation to the BBB and the immune system and to routes of pathogen entry are discussed below, together with other environmental risk factors that affect BBB integrity.
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