Author: Zeng, Zhengyang; Zhang, Runhong; Hong, Wei; Cheng, Yuting; Wang, Huijuan; Lang, Yange; Ji, Zhenglin; Wu, Yingliang; Li, Wenxin; Xie, Youli; Cao, Zhijian
Title: Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1 Document date: 2018_1_1
ID: zilqyfjl_45
Snippet: Six putative peptides from the venomous cDNA library of the scorpion E. validus were identified as candidate antimicrobial peptides by bioinformatics analysis of their sequences as well as evaluation of their amphipathy and positively charged α-helix structures, which are the classical structure features of antimicrobial peptides. Precursor structure analysis of the six scorpion-derived peptides is shown in Figure 1 . The details of open-readin.....
Document: Six putative peptides from the venomous cDNA library of the scorpion E. validus were identified as candidate antimicrobial peptides by bioinformatics analysis of their sequences as well as evaluation of their amphipathy and positively charged α-helix structures, which are the classical structure features of antimicrobial peptides. Precursor structure analysis of the six scorpion-derived peptides is shown in Figure 1 . The details of open-reading frames and amino acid sequences are shown. The candidate peptides were screened for viral inactivation against HSV-1 by plaque reduction assay (PRA) in Vero cells.
Search related documents:
Co phrase search for related documents- amino acid and bioinformatic analysis: 1, 2, 3, 4, 5, 6, 7
- amino acid and candidate peptide: 1, 2, 3, 4, 5
- amino acid and cdna library: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- amino acid and classical structure: 1, 2
- amino acid and α helix structure: 1, 2, 3
- amino acid and putative peptide: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- amino acid and reduction assay: 1, 2
- amino acid and scorpion cdna library: 1
- amino acid and structure analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48
- amino acid and venomous scorpion cdna library: 1
- amino acid and Vero cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- amino acid and viral inactivation: 1
- amino acid sequence and antimicrobial peptide: 1, 2
- amino acid sequence and bioinformatic analysis: 1, 2
- amino acid sequence and candidate peptide: 1
- amino acid sequence and cdna library: 1, 2, 3, 4, 5, 6, 7, 8, 9
- amino acid sequence and putative peptide: 1, 2, 3, 4
- amino acid sequence and structure analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- amino acid sequence and Vero cell: 1, 2
Co phrase search for related documents, hyperlinks ordered by date