Author: Carter, Chris J.
Title: Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s Disease Document date: 2017_9_28
ID: tmpidjrp_110
Snippet: In a Greek study, H. pylori-infected AD patients receiving the triple eradication regime (omeprazole, clarithromycin and amoxicillin) showed improved cognitive and functional status parameters where bacterial eradication was successful [280] . H. pylori eradication in AD patients with peptic ulcer was also associated with a decreased risk of AD progression in a Taiwanese study [281] . A Canadian study has shown that antibiotic treatment (doxycycl.....
Document: In a Greek study, H. pylori-infected AD patients receiving the triple eradication regime (omeprazole, clarithromycin and amoxicillin) showed improved cognitive and functional status parameters where bacterial eradication was successful [280] . H. pylori eradication in AD patients with peptic ulcer was also associated with a decreased risk of AD progression in a Taiwanese study [281] . A Canadian study has shown that antibiotic treatment (doxycycline and rifampin) reduced the rate of cognitive decline (Standardized AD Assessment Scale cognitive subscale) in mild to moderate AD [282] . Although few in number, these are perhaps the only studies with any demonstrated effectiveness in slowing the progression of AD.
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