Author: Cao, Wei; Liu, Xiaosheng; Bai, Tao; Fan, Hongwei; Hong, Ke; Song, Hui; Han, Yang; Lin, Ling; Ruan, Lianguo; Li, Taisheng
Title: High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019 Document date: 2020_3_21
ID: u3gmpklc_7
Snippet: The diagnosis was modified to COVID-19, severe type. Highdose IVIg was started on January 28 (hospital day 7) at 25 g/d for 5 days (body weight 66 kg). Moxifloxacin was continued until February 2. On the same day after IVIg infusion, the patient became afebrile. No adverse event was reported. Over the next few days, his clinical status gradually improved. The supplemental oxygen was discontinued, and his oxygen saturation level returned to 97%-98.....
Document: The diagnosis was modified to COVID-19, severe type. Highdose IVIg was started on January 28 (hospital day 7) at 25 g/d for 5 days (body weight 66 kg). Moxifloxacin was continued until February 2. On the same day after IVIg infusion, the patient became afebrile. No adverse event was reported. Over the next few days, his clinical status gradually improved. The supplemental oxygen was discontinued, and his oxygen saturation level returned to 97%-98% on February 3 when breathing ambient air. Test results on February 5 showed recovered lymphocyte count to 1.6 ×10 9 /L. The ESR decreased to 31 mm/h, and hsCRP returned to normal range. The CT scan showed partial resolution of previous lesions ( Figure 1A ). Two consecutive oropharyngeal swabs on February 2 and 3 were both negative for 2019-nCoV. The patient was discharged on February 5.
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