Author: Hu, Song; Jiang, Li-Bin; Zou, Xiao-Jing; Yi, Wei; Tian, De-Ying
Title: Hepatitis B virus upregulates host expression of a-1,2-mannosidases via the PPARa pathway Document date: 2016_11_21
ID: w5m23ikh_28
Snippet: speculate that the expression of PPAR subtypes could be altered in different cell types, which could be at least partially responsible for the difference between our findings and the previous studies. We also tested the effect of MK886 on the expression of α-1,2mannosidases in AD38 cells. Increases in the levels of MAN1C1 were inhibited by MK886 in AD38 cells. Therefore, we speculate that the effects of the HBV envelope protein in upregulating t.....
Document: speculate that the expression of PPAR subtypes could be altered in different cell types, which could be at least partially responsible for the difference between our findings and the previous studies. We also tested the effect of MK886 on the expression of α-1,2mannosidases in AD38 cells. Increases in the levels of MAN1C1 were inhibited by MK886 in AD38 cells. Therefore, we speculate that the effects of the HBV envelope protein in upregulating the expression of class â… Î±-mannosidases are closely associated with the PPARα pathway.
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