Author: Zeng, Zhengyang; Zhang, Runhong; Hong, Wei; Cheng, Yuting; Wang, Huijuan; Lang, Yange; Ji, Zhenglin; Wu, Yingliang; Li, Wenxin; Xie, Youli; Cao, Zhijian
Title: Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1 Document date: 2018_1_1
ID: zilqyfjl_66
Snippet: Unfortunately, Eval418 scarcely exhibited any inhibition of plaque formation when pre-incubated with cells before infection or added to cells after infection. In addition, Eval418 only exerted a weak inhibition when added to cells during the viral entry step. The results of confocal microscopy and flow cytometry analyses showed that Eval418 exerted an extremely poor cellular uptake as no visible FITC-labeled Eval418 was detected in the incubated .....
Document: Unfortunately, Eval418 scarcely exhibited any inhibition of plaque formation when pre-incubated with cells before infection or added to cells after infection. In addition, Eval418 only exerted a weak inhibition when added to cells during the viral entry step. The results of confocal microscopy and flow cytometry analyses showed that Eval418 exerted an extremely poor cellular uptake as no visible FITC-labeled Eval418 was detected in the incubated cells.
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