Selected article for: "lung tissue and molecular diagnostic"
Author: Seo, Sachiko; Waghmare, Alpana; Scott, Emily M; Xie, Hu; Kuypers, Jane M; Hackman, Robert C.; Campbell, Angela P.; Choi, Su-Mi; Leisenring, Wendy M.; Jerome, Keith R.; Englund, Janet A.; Boeckh, Michael
Title: Human rhinovirus detection in the lower respiratory tract of hematopoietic cell transplant recipients: association with mortality
  • Document date: 2017_6_23
    • ID: t7qk6evo_32
    Snippet: In conclusion, we provide further evidence that HRV is a serious pathogen in the lower respiratory tract of HCT recipients. This conclusion is supported by similar outcomes of patients with HRV in the BAL compared to those with well-established respiratory pathogens such as RSV and influenza virus and by the presence of HRV in lung tissue. The data are also consistent with the recent literature on HRV in other clinical settings, which supports a .....
    Document: In conclusion, we provide further evidence that HRV is a serious pathogen in the lower respiratory tract of HCT recipients. This conclusion is supported by similar outcomes of patients with HRV in the BAL compared to those with well-established respiratory pathogens such as RSV and influenza virus and by the presence of HRV in lung tissue. The data are also consistent with the recent literature on HRV in other clinical settings, which supports a potential causal role in serious clinical disease, 1 and agree with earlier studies in HCT recipients carried out prior to the use of molecular diagnostic techniques. 6, 7 However, while these data are supportive of a pathogenic role of HRV, ultimate proof could best be provided by randomized placebo-controlled trials. These data provide the rationale for the rapid development and clinical evaluation of new therapeutics.

    Search related documents:
    Co phrase search for related documents
    • clinical disease and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • clinical disease and new therapeutic: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • clinical evaluation and lung tissue: 1, 2, 3, 4
    • clinical evaluation and new therapeutic: 1, 2, 3, 4, 5, 6, 7, 8
    • clinical setting and lung tissue: 1, 2, 3, 4, 5, 6
    • clinical setting and new therapeutic: 1, 2, 3, 4, 5, 6
    • diagnostic technique and molecular diagnostic technique: 1, 2, 3, 4, 5, 6
    • early study and lung tissue: 1, 2, 3, 4, 5
    • early study and new therapeutic: 1, 2, 3
    • influenza RSV virus and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8
    • influenza RSV virus and new therapeutic: 1, 2
    • lung tissue and new therapeutic: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12