Author: Joseph R Fauver; Mary E. Petrone; Emma B Hodcroft; Kayoko Shioda; Hanna Y Ehrlich; Alexander G. Watts; Chantal B.F. Vogels; Anderson F. Brito; Tara Alpert; Anthony Muyombwe; Jafar Razeq; Randy Downing; Nagarjuna R. Cheemarla; Anne L Wyllie; Chaney C. Kalinich; Isabel Ott; Josh Quick; Nicholas J. Loman; Karla M. Neugebauer; Alexander L. Greninger; Keith R. Jerome; Pavitra Roychoundhury; Hong Xie; Lasata Shrestha; Meei-Li Huang; Virginia E. Pitzer; Akiko Iwasaki; Saad B. Omer; Kamran Khan; Isaac Bogoch; Richard A. Martinello; Ellen F. Foxman; Marie-Louise Landry; Richard A Neher; Albert I Ko; Nathan D. Grubaugh
Title: Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology Document date: 2020_3_26
ID: 8m06zdho_18
Snippet: We argue that, though simplistic, our model demonstrates the urgent need to focus control efforts in the U.S. on preventing further domestic virus spread. In China, local outbreak dynamics were highly correlated with travel between Wuhan and the outbreak dynamics therein during the early months of the epidemic . Similarly, if interstate introductions are not curtailed in the U.S. with improved surveillance measures, more robust diagnostic capabil.....
Document: We argue that, though simplistic, our model demonstrates the urgent need to focus control efforts in the U.S. on preventing further domestic virus spread. In China, local outbreak dynamics were highly correlated with travel between Wuhan and the outbreak dynamics therein during the early months of the epidemic . Similarly, if interstate introductions are not curtailed in the U.S. with improved surveillance measures, more robust diagnostic capabilities, and proper clinical care, quelling local transmission within states will be a Sisyphean task. We therefore propose that a unified effort to detect and prevent new COVID-19 cases will be essential for mitigating the risk of future domestic outbreaks. This effort must ensure that states have sufficient personal protective equipment, sample collection materials, and testing reagents, as these supplies enable effective surveillance. Finally, stateand local-level policymakers must recognize that the health and well-being of their constituents are contingent on that of the nation. If spread between states is now common, as our results indicate, the U.S. will struggle to control COVID-19 in the absence of a unified surveillance strategy.
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