Author: Cho, Sung-Yeon; Lee, Hyeon-Jeong; Lee, Dong-Gun
                    Title: Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea  Document date: 2018_2_27
                    ID: t9tysvr8_54
                    
                    Snippet: There are little data on CRV infection in HSCT patients in Korea. In a 4-year retrospective study in the authors' HSCT center from 2007 to 2011, 67 of 1,038 HSCT patients (6.5%) had 71 cases of CRV-LRTI. RSV (43.6%) was the most common pathogen of CRV-LRTI, followed by PIV (26.8%), influenza virus (19.7%), and rhinovirus (9.9%) [127] . The overall mortality rate at day 30 after CRV-LRTI was 32.8%, and high-dose steroid usage (> 1 mg/kg/day), seve.....
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: There are little data on CRV infection in HSCT patients in Korea. In a 4-year retrospective study in the authors' HSCT center from 2007 to 2011, 67 of 1,038 HSCT patients (6.5%) had 71 cases of CRV-LRTI. RSV (43.6%) was the most common pathogen of CRV-LRTI, followed by PIV (26.8%), influenza virus (19.7%), and rhinovirus (9.9%) [127] . The overall mortality rate at day 30 after CRV-LRTI was 32.8%, and high-dose steroid usage (> 1 mg/kg/day), severe immunodeficiency, and lymphopenia (absolute lymphocyte count < 200 cells/mm 3 ) were significantly associated with mortality [127] . These findings are similar to the prevalence, mortality rate, and mortality-related risk factors of CRV-LRTI in Europe and the United States.
 
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