Author: Linder, Kathleen A; McDonald, Philip J; Kauffman, Carol A; Revankar, Sanjay G; Chandrasekar, Pranatharthi H; Miceli, Marisa H
Title: Infectious Complications After Umbilical Cord Blood Transplantation for Hematological Malignancy Document date: 2019_2_22
ID: qu20hqch_18
Snippet: A total of 179 episodes of infection were reported in 55 patients; the median number of episodes per patient was 3 (range, 0-11). The greatest number of infections occurred within 30 days post-UCBT (73 episodes in 50 patients). Among these early infections, 57 (78%) occurred before neutrophil engraftment. Although fewer in number, infections continued to occur throughout the 2-year follow-up period post-UCBT; there were 51 episodes between days 3.....
Document: A total of 179 episodes of infection were reported in 55 patients; the median number of episodes per patient was 3 (range, 0-11). The greatest number of infections occurred within 30 days post-UCBT (73 episodes in 50 patients). Among these early infections, 57 (78%) occurred before neutrophil engraftment. Although fewer in number, infections continued to occur throughout the 2-year follow-up period post-UCBT; there were 51 episodes between days 30 and 100 and 55 episodes after day 100. Viral infections were most common, followed by bacterial and fungal infections. There were no episodes of infection with protozoal or helminthic pathogens. Several different infections were present concurrently in 64 (36%) of infectious episodes, irrespective of the time posttransplant. The mean number of infectious episodes per patient ranged between 2 and 3.8 per year over the 10-year period of the study.
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