Author: Shif, Ilan; Bang, Frederik B.
Title: IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : II. BIOLOGICAL CHARACTERIZATION OF A VARIANT VIRUS MHV(C(3)H) ISOLATED FROM STOCKS OF MHV(PRI) Document date: 1970_3_31
ID: ygy9o4bj_26
Snippet: It is most unlikely that MHV(C,H) resided as a latent virus in the C3H cells: (a) the degree of the delayed destruction was dependent upon the concentration of the prevalent virus, MHV(PRI), (b) virus-free fluids or UV-inactivated MHV(PRI) had no effect in the initiation of delayed destruction or on the emergence of the new variant, and (c) the variant virus was not isolated from normal C3H cultured macrophages held in culture for as long as 1 mo.....
Document: It is most unlikely that MHV(C,H) resided as a latent virus in the C3H cells: (a) the degree of the delayed destruction was dependent upon the concentration of the prevalent virus, MHV(PRI), (b) virus-free fluids or UV-inactivated MHV(PRI) had no effect in the initiation of delayed destruction or on the emergence of the new variant, and (c) the variant virus was not isolated from normal C3H cultured macrophages held in culture for as long as 1 month.
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