Selected article for: "disease outbreak and laboratory testing"
Author: Huh, Hee Jae; Ko, Jae-Hoon; Kim, Young-Eun; Park, Chang-Hun; Hong, Geehay; Choi, Rihwa; Yu, Shinae; Cho, Sun Young; Kang, Ji-Man; Lee, Myoung-Keun; Ki, Chang-Seok; Kang, Eun-Suk; Lee, Nam Yong; Kim, Jong-Won; Kim, Yae-Jean; Ha, Young Eun; Kang, Cheol-In; Chung, Doo Ryeon; Peck, Kyong Ran; Song, Jae-Hoon
Title: Importance of Specimen Type and Quality in Diagnosing Middle East Respiratory Syndrome
  • Document date: 2016_11_1
    • ID: s958dq2q_1
    Snippet: Dear Editor, From May to July 2015, there was a hospital-associated outbreak in South Korea reporting 186 laboratory-confirmed cases. Highly sensitive and specific laboratory diagnostic tests are important for the control of Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks. Clinical guidelines for the molecular diagnosis of MERS-CoV are based on the interim recommendations from the WHO, the United States Centers for Disease Contr.....
    Document: Dear Editor, From May to July 2015, there was a hospital-associated outbreak in South Korea reporting 186 laboratory-confirmed cases. Highly sensitive and specific laboratory diagnostic tests are important for the control of Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks. Clinical guidelines for the molecular diagnosis of MERS-CoV are based on the interim recommendations from the WHO, the United States Centers for Disease Control and Prevention (US CDC), and other available resources [1] [2] [3] [4] . To date, only a few studies have reported the molecular detection of this disease during an outbreak [5] [6] [7] [8] . To validate the current guidelines for MERS-CoV laboratory testing, we retrospectively reviewed the results of MERS-CoV real-time reverse transcription (rRT)-PCR assays in the Korean tertiary care hospital with the largest number of MERS cases (Samsung Medical Center). The Institutional Review Board of the Samsung Medical Center (IRB #2015-06-201) approved this study.

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