Selected article for: "CMV human cytomegalovirus and human cytomegalovirus"

Author: Linder, Kathleen A; McDonald, Philip J; Kauffman, Carol A; Revankar, Sanjay G; Chandrasekar, Pranatharthi H; Miceli, Marisa H
Title: Infectious Complications After Umbilical Cord Blood Transplantation for Hematological Malignancy
  • Document date: 2019_2_22
  • ID: qu20hqch_2
    Snippet: Prolonged neutropenia is a well recognized risk factor for severe infections [5] . Patients receiving UCBT appear to be at increased risk compared with allogeneic HCT recipients, perhaps due to delayed engraftment [6] [7] [8] . Infection is estimated to cause 35%-50% of nonrelapse mortality in patients after UCBT, compared with 8%-22% after allogeneic HCT [2, 5, 6, [9] [10] [11] [12] . Viral infections, especially cytomegalovirus (CMV), and human.....
    Document: Prolonged neutropenia is a well recognized risk factor for severe infections [5] . Patients receiving UCBT appear to be at increased risk compared with allogeneic HCT recipients, perhaps due to delayed engraftment [6] [7] [8] . Infection is estimated to cause 35%-50% of nonrelapse mortality in patients after UCBT, compared with 8%-22% after allogeneic HCT [2, 5, 6, [9] [10] [11] [12] . Viral infections, especially cytomegalovirus (CMV), and human herpesvirus 6 (HHV- 6) , have been associated with increased morbidity and mortality post-UCBT [6, 13] . We sought to characterize the infectious complications and outcomes of patients who received a UCBT in our institutions over a 10-year period.

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