Author: Stenglein, Mark D.; Sanders, Chris; Kistler, Amy L.; Ruby, J. Graham; Franco, Jessica Y.; Reavill, Drury R.; Dunker, Freeland; DeRisi, Joseph L.
Title: Identification, Characterization, and In Vitro Culture of Highly Divergent Arenaviruses from Boa Constrictors and Annulated Tree Boas: Candidate Etiological Agents for Snake Inclusion Body Disease Document date: 2012_8_14
ID: vkhg20he_25
Snippet: The arenaviruses are a family of viruses that had been previously believed to infect only mammals (21, 25, 26, 42) . Rodents are thought to be the natural hosts of arenaviruses, and individual virus species are associated with specific hosts. Infection is typically chronic and asymptomatic in rodents. However, when arenaviruses zoonotically infect humans or other mammals, severe disease can result. Scientific study has focused on these viruses fo.....
Document: The arenaviruses are a family of viruses that had been previously believed to infect only mammals (21, 25, 26, 42) . Rodents are thought to be the natural hosts of arenaviruses, and individual virus species are associated with specific hosts. Infection is typically chronic and asymptomatic in rodents. However, when arenaviruses zoonotically infect humans or other mammals, severe disease can result. Scientific study has focused on these viruses for two principal reasons: (i) some of these viruses (e.g., LASV) can cause fatal hemorrhagic fever in humans, and (ii) the arenavirus LCMV provides an excellent tool to study the immune response in its natural host, Mus musculus (43) . Infection of members of the Reptilia class of animals demonstrates that arenavirus infection is not limited to mammals.
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