Title: Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence Document date: 1993_3_1
ID: qt44izzh_23
Snippet: To determine whether defined regions of the TGN38 molecule contained information that was sufficient for TGN localization, chimeric proteins were constructed by exchanging domains between TGN38 and the Tac antigen (interleukin-2 receptor c~ chain, Leonard et al., 1984) (Fig. 1, top) . The Tac antigen is a type I integral membrane protein with a topological organization similar to that of TGN38 ( Fig. 1, top). Unlike TGN38, however, Tac is primari.....
Document: To determine whether defined regions of the TGN38 molecule contained information that was sufficient for TGN localization, chimeric proteins were constructed by exchanging domains between TGN38 and the Tac antigen (interleukin-2 receptor c~ chain, Leonard et al., 1984) (Fig. 1, top) . The Tac antigen is a type I integral membrane protein with a topological organization similar to that of TGN38 ( Fig. 1, top). Unlike TGN38, however, Tac is primarily localized to the cell surface (Leonard et al., 1984; Weissman et al., 1986; Bonifacino et al., 1990) .
Search related documents:
Co phrase search for related documents- cell surface and define region: 1, 2
- cell surface and membrane protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell surface and receptor chain: 1, 2, 3, 4, 5, 6
- cell surface and Tac antigen: 1, 2
- cell surface and TGN localization: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- cell surface and TGN localization sufficient information: 1, 2
- chimeric protein and membrane protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- chimeric protein and Tac antigen: 1
- chimeric protein and TGN localization: 1, 2, 3, 4, 5, 6
- define region and membrane protein: 1, 2, 3
- domain exchange and membrane protein: 1
- membrane protein and receptor chain: 1, 2
- membrane protein and Tac antigen: 1, 2
- membrane protein and TGN localization: 1, 2, 3, 4, 5, 6, 7, 8
- membrane protein and TGN localization sufficient information: 1
- membrane protein and TGN38 molecule: 1
- membrane protein and topological organization: 1
- receptor chain and Tac antigen: 1
- receptor chain and TGN localization: 1
Co phrase search for related documents, hyperlinks ordered by date