Author: Cho, Sung-Yeon; Lee, Hyeon-Jeong; Lee, Dong-Gun
Title: Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea Document date: 2018_2_27
ID: t9tysvr8_63
Snippet: Tuberculosis (TB) is an important opportunistic infection among HSCT recipients, in whom its incidence is 2-to 40-fold higher than that in the general population; however, this is lower than in solid-organ-transplant patients [145] [146] [147] . HSCT recipients are immunosuppressed as a result of their hematologic disease, chemotherapy, radiotherapy, immunosuppressive agents, and GVHD [146] . Several risk factors for the development of TB after H.....
Document: Tuberculosis (TB) is an important opportunistic infection among HSCT recipients, in whom its incidence is 2-to 40-fold higher than that in the general population; however, this is lower than in solid-organ-transplant patients [145] [146] [147] . HSCT recipients are immunosuppressed as a result of their hematologic disease, chemotherapy, radiotherapy, immunosuppressive agents, and GVHD [146] . Several risk factors for the development of TB after HSCT have been reported, including acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndrome, busulfan, cyclophosphamide, TBI, corticosteroid therapy, HLA-mismatched transplant, GVHD, or a history of TB infection [148] . Of HSCT patients who develop TB, 80% and 20% had undergone allogeneic and autologous transplant, respectively.
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