Author: Vere Hodge, R Anthony
Title: Meeting report: 30th International Conference on Antiviral Research, in Atlanta, GA, USA Document date: 2018_6_28
ID: tudwns0r_53
Snippet: Dating back to within the Neolithic (late stone age) period, a large DNA data set includes the genomes of 230 West Eurasians who lived between 6500 and 300 BC, including 163 with newly reported data. 5 To answer this question, a phylogenetic tree was created in collaboration with Nels Elde and Alesia McKeown (University of Utah) from many clinical samples, most of which were unpassaged clinical isolates of RVs, types A, B and C. Samples from all .....
Document: Dating back to within the Neolithic (late stone age) period, a large DNA data set includes the genomes of 230 West Eurasians who lived between 6500 and 300 BC, including 163 with newly reported data. 5 To answer this question, a phylogenetic tree was created in collaboration with Nels Elde and Alesia McKeown (University of Utah) from many clinical samples, most of which were unpassaged clinical isolates of RVs, types A, B and C. Samples from all serotypes were represented. Preliminary information suggested an emergence of RV-C from the RV-A, about 3000-5000 years ago. Ann generously added interesting unpublished data which has led to a probable date for this divergence. The emergence of RV-C may explain why the Cys 529 protein has become so dominant in the modern human population but it does not account for the early appearance of this variant in ancient human DNA prior to 'out of Africa'.
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