Author: Shim, Yoon Hee; Kim, Hae Soon; Sohn, Sejung; Hong, Young Mi
Title: Insertion/Deletion Polymorphism of Angiotensin Converting Enzyme Gene in Kawasaki Disease Document date: 2006_4_20
ID: wup6tig0_3
Snippet: Angiotensin converting enzyme (ACE) breaks down the potent vasodilator, bradykinin to its inactivate metabolite and catalyzes angiotensin I to angiotensin II. Angiotensin II promotes hyperplasia and hypertrophy of vascular smooth muscle cells, induces the production of proinflammatory cytokines and causes endothelial dysfunction by free radical generation. By playing an important role in cardiovascular regulatory system, ACE gene has been propose.....
Document: Angiotensin converting enzyme (ACE) breaks down the potent vasodilator, bradykinin to its inactivate metabolite and catalyzes angiotensin I to angiotensin II. Angiotensin II promotes hyperplasia and hypertrophy of vascular smooth muscle cells, induces the production of proinflammatory cytokines and causes endothelial dysfunction by free radical generation. By playing an important role in cardiovascular regulatory system, ACE gene has been proposed to be associated with various cardiovascular diseases, such as ischemic heart disease, hypertrophic cardiomyopathy, idiopathic dilated cardiomyopathy, and vascular hypertrophy (14) . Among the different ACE genetic loci, the insertion/deletion polymorphism coded within intron 16 has been studied in many literature to find the association with such diseases.
Search related documents:
Co phrase search for related documents- ACE enzyme and cardiovascular disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54
- ACE enzyme and disease association: 1, 2, 3, 4, 5, 6
- ACE enzyme and endothelial dysfunction: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- ACE enzyme and endothelial dysfunction cause: 1
- ACE enzyme and heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32
- ACE enzyme and II angiotensin: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- ACE enzyme and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- ACE enzyme and insertion deletion: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- ACE enzyme and insertion deletion polymorphism: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- ACE enzyme and ischemic heart disease: 1, 2, 3
- ACE enzyme and literature study: 1, 2
- ACE enzyme and muscle cell: 1
- ACE enzyme and proinflammatory cytokine: 1, 2, 3
- ACE enzyme and regulatory system: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- ACE enzyme and smooth muscle cell: 1
- ACE enzyme convert and Angiotensin ACE enzyme convert: 1, 2
- ACE enzyme convert and II angiotensin: 1
- ACE enzyme convert and important role: 1
- ACE gene and cardiovascular disease: 1
Co phrase search for related documents, hyperlinks ordered by date