Author: Assiri, Abdullah M.; Biggs, Holly M.; Abedi, Glen R.; Lu, Xiaoyan; Bin Saeed, Abdulaziz; Abdalla, Osman; Mohammed, Mutaz; Al-Abdely, Hail M.; Algarni, Homoud S.; Alhakeem, Raafat F.; Almasri, Malak M.; Alsharef, Ali A.; Nooh, Randa; Erdman, Dean D.; Gerber, Susan I.; Watson, John T.
Title: Increase in Middle East Respiratory Syndrome-Coronavirus Cases in Saudi Arabia Linked to Hospital Outbreak With Continued Circulation of Recombinant Virus, July 1–August 31, 2015 Document date: 2016_8_3
ID: qxk97kdz_3
Snippet: Middle East respiratory syndrome coronavirus (MERS-CoV), first detected in 2012 in Saudi Arabia (SA), is known to cause acute respiratory illness in humans. To date, approximately 80% of MERS-CoV cases have been reported by SA. The spectrum of clinical illness associated with MERS-CoV infection is broad and ranges from asymptomatic infection to severe pneumonia, multiorgan failure, and death. The overall case fatality rate is approximately 35%-40.....
Document: Middle East respiratory syndrome coronavirus (MERS-CoV), first detected in 2012 in Saudi Arabia (SA), is known to cause acute respiratory illness in humans. To date, approximately 80% of MERS-CoV cases have been reported by SA. The spectrum of clinical illness associated with MERS-CoV infection is broad and ranges from asymptomatic infection to severe pneumonia, multiorgan failure, and death. The overall case fatality rate is approximately 35%-40%, and individuals with underlying medical comorbidities appear to be at increased risk for infection, severe illness, and death [1] . The epidemiology of MERS-CoV has been characterized by intermittent sporadic cases, occasional large healthcare-associated outbreaks, and transmission to close household contacts of cases [2, 3] . Zoonotic transmission is suspected as the source of primary infection in humans, with increasing evidence supporting the importance of dromedary camels in SA [1, 4] .
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