Selected article for: "host defence and immune defence system"

Author: Min Cao; Dandan Zhang; Youhua Wang; Yunfei Lu; Xiangdong Zhu; Ying Li; Honghao Xue; Yunxiao Lin; Min Zhang; Yiguo Sun; Zongguo Yang; Jia Shi; Yi Wang; Chang Zhou; Yidan Dong; Ping Liu; Steven M Dudek; Zhen Xiao; Hongzhou Lu; Longping Peng
Title: Clinical Features of Patients Infected with the 2019 Novel Coronavirus (COVID-19) in Shanghai, China
  • Document date: 2020_3_6
  • ID: dmud2zf7_48
    Snippet: Interestingly, a noticeable increase of glutathione reductase (GR) level occurred in 40.2% of the COVID-19 patients in our cohort, while ALT and AST are normal in most patients. GR is an essential enzyme that recycles oxidized glutathione back to the reduced form 13 . GR is known to participate in an oxidative defence system required for effective immune responses against bacteria 14 15 . Whether GR is involved in host defence systems against vir.....
    Document: Interestingly, a noticeable increase of glutathione reductase (GR) level occurred in 40.2% of the COVID-19 patients in our cohort, while ALT and AST are normal in most patients. GR is an essential enzyme that recycles oxidized glutathione back to the reduced form 13 . GR is known to participate in an oxidative defence system required for effective immune responses against bacteria 14 15 . Whether GR is involved in host defence systems against viruses such as SARS-Cov-2 remains to be determined.

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