Selected article for: "high rate and unclear remain"
Author: Linder, Kathleen A; McDonald, Philip J; Kauffman, Carol A; Revankar, Sanjay G; Chandrasekar, Pranatharthi H; Miceli, Marisa H
Title: Infectious Complications After Umbilical Cord Blood Transplantation for Hematological Malignancy
  • Document date: 2019_2_22
    • ID: qu20hqch_43
    Snippet: Despite prior pediatric studies that have demonstrated decreased risk of GVHD after UCBT, we saw a high rate of GVHD in our cohort (61%), and 5 patients died from sequelae of severe/refractory GVHD [3] . We observed a higher rate of acute GVHD than chronic GVHD in this population, as has been previously described [39] . It is possible that higher rates of acute GVHD after UCBT are associated with greater HLA mismatch; however, the exact mechanism.....
    Document: Despite prior pediatric studies that have demonstrated decreased risk of GVHD after UCBT, we saw a high rate of GVHD in our cohort (61%), and 5 patients died from sequelae of severe/refractory GVHD [3] . We observed a higher rate of acute GVHD than chronic GVHD in this population, as has been previously described [39] . It is possible that higher rates of acute GVHD after UCBT are associated with greater HLA mismatch; however, the exact mechanisms remain unclear [39, 40] .

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