Selected article for: "chain reaction and positive reaction"
Author: Cho, Sung-Yeon; Lee, Hyeon-Jeong; Lee, Dong-Gun
Title: Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea
  • Document date: 2018_2_27
    • ID: t9tysvr8_34
    Snippet: If PCP is clinically suspected, CT, bronchoscopy, and BAL should be performed as early as possible. In a retrospective study of bronchial washings or BAL fluid from non-human immunodeficiency virus (HIV)-infected patients suspected of respiratory infection, among the 169 polymerase chain reaction (PCR)-positive patients, 63.3% were classified as PCP and 46.7% as non-PCP. The majority of patients (84%) in the non-PCP group recovered without treatm.....
    Document: If PCP is clinically suspected, CT, bronchoscopy, and BAL should be performed as early as possible. In a retrospective study of bronchial washings or BAL fluid from non-human immunodeficiency virus (HIV)-infected patients suspected of respiratory infection, among the 169 polymerase chain reaction (PCR)-positive patients, 63.3% were classified as PCP and 46.7% as non-PCP. The majority of patients (84%) in the non-PCP group recovered without treatment for PCP [65] . In two recent meta-analyses, the sensitivity and specificity of quantitative PCR (qPCR) assays were superior to those of non-qPCR assays [66, 67] . The serum β-D-glucan test result has a high negative-predictive value but is not useful for the follow-up of PCP [68] . The prognosis is worse in the presence of concomitant infectious diseases, particularly CMV, Aspergillus, and so on. Steroids can be used as an adjunctive therapy in patients with hypoxia (PaO 2 ≤ 70 mmHg or PAO 2 -PaO 2 ≥ 35 mmHg).

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