Author: Cho, Sung-Yeon; Lee, Hyeon-Jeong; Lee, Dong-Gun
Title: Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea Document date: 2018_2_27
ID: t9tysvr8_55
Snippet: The average mortality rate of RSV-LRTI is 32% (range, 0% to 70%) in international studies, and the major risk factors for progression to LRTI are lymphopenia, old age, mismatched/unrelated donor, and neutropenia [128, 129] . In cases of PIV-LRTI, the overall mortality rate is 10% to 30%, and high-level corticosteroid exposure, neutropenia, lymphopenia, and early onset after HSCT are the major risk factors for LRTI [129] [130] [131] . The rate of .....
Document: The average mortality rate of RSV-LRTI is 32% (range, 0% to 70%) in international studies, and the major risk factors for progression to LRTI are lymphopenia, old age, mismatched/unrelated donor, and neutropenia [128, 129] . In cases of PIV-LRTI, the overall mortality rate is 10% to 30%, and high-level corticosteroid exposure, neutropenia, lymphopenia, and early onset after HSCT are the major risk factors for LRTI [129] [130] [131] . The rate of progression of influenza to LRTI is 25% to 28% and the overall mortality rate is 25% to 58% [132] [133] [134] . The risk factors for progression to influenza-LRTI are early onset after HSCT, lymphopenia, old age, neutropenia, and delayed antiviral administration [132] [133] [134] . In cases of rhinovirus, most infections are asymptomatic, less than 10% of patients progress to definite pneumonia, and the mortality rate is < 10% [135, 136] . In addition, human metapneumovirus, adenovirus, coronavirus, and bocavirus can cause URTIs and LRTIs in HSCT patients [129, 137] .
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