Laboratory epidemiology of respiratory viruses in a large children's hospital: A STROBE-compliant article

Ye, Sheng; Wang, Tianlin

In multivariable logistic regression analysis, age was independently associated with positive result for adenovirus (Table 5) . With 1 year increase in age, the odds of positive result increased by 2% (odds ratio [OR]: 1.02; 95% confidence interval [CI]: 1.01-1.04; P = .001). Male gender was associated with higher risk of positive for adenovirus (OR: 1.10; 95% CI: 1.02-1.20; P = .017). The type of sample was not significantly associated with positive result. As compared with the autumn, samples collected in the summer were more likely to be positive for adenovirus (OR: 14.48; 95% CI: 12.17-17.34; P < .001), whereas the winter was associated with lower risk of positive result (OR: 0.81; 95% CI: 0.68-0.97; P = .018). For the test of influenza A (Table 6) , age was independently associated with positive result. With 1 year increase in age, the odds of positive result increased by 12% (OR: 1.12; 95% CI: 1.11-1.13; P < .001). Male gender was not associated with risk of positive results. Samples obtained by throat swab was less likely to report positive result for influenza A (OR: 0.68; 95% CI: 0.62-0.76; P < .001). As compared with the autumn, samples obtained in summer were more likely to be positive for influenza A (OR: 0.06; 95% CI: 0.02-0.12; P < .001), whereas the winter was associated Comparing baseline characteristics of samples tested negative and positive for adenovirus. Note: there were 4 samples with missing values on the results. They were counted in the total column, but not counted in the negative and positive columns. In winter, the samples were more likely to be positive for influenza A (0.72 vs 0.37; P < .001). Sputum samples were more likely to be positive for influenza A (0.82 vs 0.75; P < .001). Table 3 Comparing baseline characteristics of samples tested negative and positive for influenza B virus.