Author: Choi, Kang-Seuk
Title: Newcastle disease virus vectored vaccines as bivalent or antigen delivery vaccines Document date: 2017_7_26
ID: vk59ghjm_25
Snippet: Administration of live attenuated AIV vaccines to poultry is strictly prohibited due to the risk of emerging variants arising from reversion to virulence via antigenic drift or antigenic shift in the presence of circulating field viruses [8] . NDV-vectored AIV vaccines are bivalent live attenuated vaccines that are suitable for mass vaccination of poultry on a commercial scale and have a proven safety profile. Basically, NDV-vectored AI vaccines .....
Document: Administration of live attenuated AIV vaccines to poultry is strictly prohibited due to the risk of emerging variants arising from reversion to virulence via antigenic drift or antigenic shift in the presence of circulating field viruses [8] . NDV-vectored AIV vaccines are bivalent live attenuated vaccines that are suitable for mass vaccination of poultry on a commercial scale and have a proven safety profile. Basically, NDV-vectored AI vaccines are designed to express the HA protein of AIV, which is critical for protection [45, 46] (Table 3) .
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