Selected article for: "cellular receptor and target cell"

Author: Dejnirattisai, Wanwisa; Webb, Andrew I.; Chan, Vera; Jumnainsong, Amonrat; Davidson, Andrew; Mongkolsapaya, Juthathip; Screaton, Gavin
Title: Lectin Switching During Dengue Virus Infection
  • Document date: 2011_6_15
  • ID: qos9vu3r_3
    Snippet: Recent reports have identified monocytes as a major cell target of viral replication, and heparin sulfates, DC-SIGN, mannose receptor, and other glycoproteins have been proposed as cellular receptors for DENV [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] . DC-SIGN polymorphism has been shown to be associated with the disease severity [19] . CLEC5A has also recently been described as a proinflammatory receptor for DENV that contributes .....
    Document: Recent reports have identified monocytes as a major cell target of viral replication, and heparin sulfates, DC-SIGN, mannose receptor, and other glycoproteins have been proposed as cellular receptors for DENV [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] . DC-SIGN polymorphism has been shown to be associated with the disease severity [19] . CLEC5A has also recently been described as a proinflammatory receptor for DENV that contributes to lethal disease in a mouse model [20] .

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