Selected article for: "MONT subgroup and virus negative MONT subgroup"
Author: Kim, Chang-Keun; Callaway, Zak; Park, Jin-Sung; Nishimori, Hisashi; Ogino, Tikatoshi; Nagao, Mizuho; Fujisawa, Takao
Title: Montelukast Reduces Serum Levels of Eosinophil-Derived Neurotoxin in Preschool Asthma
  • Document date: 2018_8_30
    • ID: uzge50xu_36
    Snippet: All patients in this study were also tested for virus infection as it is well known that respiratory viral infection is the major cause of asthma exacerbation in children. 27 We detected virus in about half of the treated subjects and reduction in sEDN levels was significantly larger in the virus-negative subgroup of the MONT group, indicating that virus infection may have hindered the effect of montelukast (Supplementary Fig. S1 ). However, EDN .....
    Document: All patients in this study were also tested for virus infection as it is well known that respiratory viral infection is the major cause of asthma exacerbation in children. 27 We detected virus in about half of the treated subjects and reduction in sEDN levels was significantly larger in the virus-negative subgroup of the MONT group, indicating that virus infection may have hindered the effect of montelukast (Supplementary Fig. S1 ). However, EDN levels still significantly decreased in virus-positive MONT subgroups (data not shown), which may have resulted in the same levels of improvement in ACD in the virus-positive and -negative subgroups (Supplementary Fig. S2 ).

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