Selected article for: "commonality hypothesis and human pathway"

Author: Kshirsagar, Meghana; Carbonell, Jaime; Klein-Seetharaman, Judith
Title: Multitask learning for host–pathogen protein interactions
  • Document date: 2013_7_1
  • ID: sdgt2ms5_24
    Snippet: The commonality hypothesis suggests that the pathway memberships of human proteins from interactions should be similar across tasks. We define a pathway-summary function S, which aggregates all pathway vectors for a given task T s . Because our hypothesis is about interactions, we only consider pathway vectors of positive examples. Let X þ s , X þ t represent the set of positive examples from tasks T s and T t ; let n þ s , n þ t be their siz.....
    Document: The commonality hypothesis suggests that the pathway memberships of human proteins from interactions should be similar across tasks. We define a pathway-summary function S, which aggregates all pathway vectors for a given task T s . Because our hypothesis is about interactions, we only consider pathway vectors of positive examples. Let X þ s , X þ t represent the set of positive examples from tasks T s and T t ; let n þ s , n þ t be their sizes. In Figure 2 , we depict the aggregation done by S. Mathematically, we have

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