Selected article for: "experimental study and host protein"

Author: Kshirsagar, Meghana; Carbonell, Jaime; Klein-Seetharaman, Judith
Title: Multitask learning for host–pathogen protein interactions
  • Document date: 2013_7_1
  • ID: sdgt2ms5_47
    Snippet: For Salmonella typhi, we used the list of 62 interacting protein pairs reported in Schleker et al. (2012) , which were obtained by the authors by manual literature curation. These interactions come from small-scale experiments. The other three PPI interaction datasets were obtained from the PHISTO database. Most of the reported interactions for these three bacterial species come from a single high-throughput experimental study reported in Dyer et.....
    Document: For Salmonella typhi, we used the list of 62 interacting protein pairs reported in Schleker et al. (2012) , which were obtained by the authors by manual literature curation. These interactions come from small-scale experiments. The other three PPI interaction datasets were obtained from the PHISTO database. Most of the reported interactions for these three bacterial species come from a single high-throughput experimental study reported in Dyer et al. (2010) . While F.tularensis, S.typhi and Y.pestis are gram-negative gamma-protobacteria, B.anthracis is a gram-positive bacteria. The number of unique proteins in each bacterial species, the sizes of all datasets and the number of all possible host-pathogen protein pairs are listed in Table 1 .

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