Author: Dejnirattisai, Wanwisa; Webb, Andrew I.; Chan, Vera; Jumnainsong, Amonrat; Davidson, Andrew; Mongkolsapaya, Juthathip; Screaton, Gavin
Title: Lectin Switching During Dengue Virus Infection Document date: 2011_6_15
ID: qos9vu3r_38
Snippet: During natural dengue infection, mosquito saliva containing DENV particles is injected into the skin during a blood meal. Skin-resident immature DCs have been proposed to be the primary site of infection for insect-derived DENV [25] . The primary receptor on DCs for dengue virus is believed to be DC-SIGN. DC-SIGN binds N-linked high-mannose oligosaccharides, including glycans with terminal fucose residues that include the blood group Lewis x and .....
Document: During natural dengue infection, mosquito saliva containing DENV particles is injected into the skin during a blood meal. Skin-resident immature DCs have been proposed to be the primary site of infection for insect-derived DENV [25] . The primary receptor on DCs for dengue virus is believed to be DC-SIGN. DC-SIGN binds N-linked high-mannose oligosaccharides, including glycans with terminal fucose residues that include the blood group Lewis x and Lewis a eptitopes [26] .
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