Author: Imai-Matsushima, Aki; Martin-Sancho, Laura; Karlas, Alexander; Imai, Seiichiro; Zoranovic, Tamara; Hocke, Andreas C.; Mollenkopf, Hans-Joachim; Berger, Hilmar; Meyer, Thomas F.
Title: Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies Document date: 2018_6_22
ID: vopbw1tl_3
Snippet: Although alveolar epithelial cell culture models have been established previously, these have been hampered by spontaneous transdifferentiation of type II to type I-like cells in vitro [10, 11] . Therefore, most experiments with primary human alveolar epithelial cells require isolation from fresh tissue and are limited by the supply of lung specimens, as well as the time and cost associated......
Document: Although alveolar epithelial cell culture models have been established previously, these have been hampered by spontaneous transdifferentiation of type II to type I-like cells in vitro [10, 11] . Therefore, most experiments with primary human alveolar epithelial cells require isolation from fresh tissue and are limited by the supply of lung specimens, as well as the time and cost associated.
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