Author: Choi, Kang-Seuk
Title: Newcastle disease virus vectored vaccines as bivalent or antigen delivery vaccines Document date: 2017_7_26
ID: vk59ghjm_26
Snippet: To date, NDV-vectored AIV vaccines have been administered to poultry in China and Mexico. In China, approximately 11.8 billion doses of NDV-vectored AIV vaccine were used to prevent HPAI during 2006-2012 [21] . The HA gene from A/ goose/Guangdong/1/1996 (H5N1) was initially incorporated into the NDV vector but was replaced with the HA gene from A/duck/Anhui/1/2006 (H5N1) in 2008, A/duck/Guangdong/ S1322/2006 (H5N1) in 2012, and, most recently, wi.....
Document: To date, NDV-vectored AIV vaccines have been administered to poultry in China and Mexico. In China, approximately 11.8 billion doses of NDV-vectored AIV vaccine were used to prevent HPAI during 2006-2012 [21] . The HA gene from A/ goose/Guangdong/1/1996 (H5N1) was initially incorporated into the NDV vector but was replaced with the HA gene from A/duck/Anhui/1/2006 (H5N1) in 2008, A/duck/Guangdong/ S1322/2006 (H5N1) in 2012, and, most recently, with A/chicken/Guizhou/4/2013 (H5N1) [47, 48] . Approximately 32 million doses of NDV-vectored AI vaccine were used in Mexico (in the form of a live vaccine and a killed vaccine) to prevent H5N2 LPAI in poultry between July 2008 and October 2008. The Mexican vaccine expresses the HA gene from low pathogenic avian influenza virus A/chicken/Mexico/435/2005 (H5N2) [49] .
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