Author: Willemsen, Anouk; Zwart, Mark P
Title: On the stability of sequences inserted into viral genomes Document date: 2019_11_14
ID: vv5gpldi_15
Snippet: Non-human adenoviruses can be used as alternative vaccine vectors, providing several advantages such as a limited host range and restricted replication in non-host species. By using bovine adenovirus type 3, a variety of antigens and cytokines were successfully expressed in vivo (Ayalew et al. 2015) . The stability of bovine adenovirus type 1 was tested by inserting the EYFP marker and subsequently passaging the recombinant virus in cell culture .....
Document: Non-human adenoviruses can be used as alternative vaccine vectors, providing several advantages such as a limited host range and restricted replication in non-host species. By using bovine adenovirus type 3, a variety of antigens and cytokines were successfully expressed in vivo (Ayalew et al. 2015) . The stability of bovine adenovirus type 1 was tested by inserting the EYFP marker and subsequently passaging the recombinant virus in cell culture (Ren et al. 2018) . Although replication of this recombinant virus was less efficient than the wild-type virus, the inserted EYFP was stable.
Search related documents:
Co phrase search for related documents- cytokine antigen and vaccine vector: 1
- cytokine antigen and wild type: 1
- host range and limited host range: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- host range and recombinant virus: 1, 2, 3, 4, 5, 6, 7, 8
- host range and recombinant virus replication: 1
- host range and vaccine vector: 1, 2, 3, 4, 5, 6
- host range and wild type: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- host range and wild type virus: 1, 2, 3, 4, 5, 6, 7, 8
- limited host range and wild type: 1
- non human adenovirus and vaccine vector: 1, 2
- non human adenovirus and wild type: 1
- recombinant virus and vaccine vector: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48
- recombinant virus and wild type: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- recombinant virus and wild type virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54
- recombinant virus replication and vaccine vector: 1
- recombinant virus replication and wild type: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- recombinant virus replication and wild type virus: 1, 2, 3, 4, 5, 6, 7, 8
- vaccine vector and wild type: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33
- vaccine vector and wild type virus: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date