Author: Willemsen, Anouk; Zwart, Mark P
Title: On the stability of sequences inserted into viral genomes Document date: 2019_11_14
ID: vv5gpldi_29
Snippet: Based on the little evidence we obtained there appears to be strong selection for genome streamlining in ssDNA viruses. After a sequence insertion, reversion to the wild-type genome size is observed in both natural and laboratory conditions. Interestingly, the nature of the insert appears to be more important than the size of the insert, indicating that the genomic context also plays an important role in the stability of ssDNA viruses......
Document: Based on the little evidence we obtained there appears to be strong selection for genome streamlining in ssDNA viruses. After a sequence insertion, reversion to the wild-type genome size is observed in both natural and laboratory conditions. Interestingly, the nature of the insert appears to be more important than the size of the insert, indicating that the genomic context also plays an important role in the stability of ssDNA viruses.
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