Author: Park, Sun Hee; Kim, Yeon-Sook; Jung, Younghee; Choi, Soo young; Cho, Nam-Hyuk; Jeong, Hye Won; Heo, Jung Yeon; Yoon, Ji Hyun; Lee, Jacob; Cheon, Shinhye; Sohn, Kyung Mok
Title: Outbreaks of Middle East Respiratory Syndrome in Two Hospitals Initiated by a Single Patient in Daejeon, South Korea Document date: 2016_6_30
ID: soiimy63_16
Snippet: The incubation period was estimated by identifying the earliest and latest possible dates of exposure and the time of symptom onset. The serial interval was estimated by identifying the time between symptom onset in the index case and symptom onset in secondary cases. Because the data were interval-censored, we fitted them to a gamma distribution and maximum-likelihood estimates were identified using the coarseDataTools package for R [18] . The p.....
Document: The incubation period was estimated by identifying the earliest and latest possible dates of exposure and the time of symptom onset. The serial interval was estimated by identifying the time between symptom onset in the index case and symptom onset in secondary cases. Because the data were interval-censored, we fitted them to a gamma distribution and maximum-likelihood estimates were identified using the coarseDataTools package for R [18] . The parametric distribution was compared with empirical cumulative density functions of the observed incubation period (the time between the midpoint of the exposure duration and symptom onset) and serial intervals. For sensitivity analysis, we estimated the parameters excluding those with possible alternative sources of exposure (Supplementary Data).
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