Author: Chow, Ken Yan Ching; Hon, Chung Chau; Hui, Raymond Kin Hi; Wong, Raymond Tsz Yeung; Yip, Chi Wai; Zeng, Fanya; Leung, Frederick Chi Ching
Title: Molecular Advances in Severe Acute Respiratory Syndrome-associated Coronavirus (SARS-CoV) Document date: 2016_11_28
ID: xuj4yymz_34
Snippet: The phylogenetic analysis of the S gene sequence between human and animal SARS-CoV likely ruled out the possibility that it is a consequence of human to animal transmission, implying the infected animals may acquired the virus from a true animal source that has yet to be identified (80 ) . This was also supported by the host-association analysis of coronaviruses based on the nucleocapsid gene (39 ) , which pinpointed that host-shifts had played a.....
Document: The phylogenetic analysis of the S gene sequence between human and animal SARS-CoV likely ruled out the possibility that it is a consequence of human to animal transmission, implying the infected animals may acquired the virus from a true animal source that has yet to be identified (80 ) . This was also supported by the host-association analysis of coronaviruses based on the nucleocapsid gene (39 ) , which pinpointed that host-shifts had played an important role in the evolution of the virus and the host. The occurrence of avian-mammal host-shift supports the hypothesis that the SARS-CoV emerged from an unknown animal coronavirus.
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