Author: Rathore, Shailendra S.; Liu, Yinghui; Yu, Haijia; Wan, Chun; Lee, MyeongSeon; Yin, Qian; Stowell, Michael H.B.; Shen, Jingshi
Title: Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE Document date: 2019_12_24
ID: pudp1eoo_18
Snippet: Thus, the juxtamembrane motif of VAMP2 is intrinsically capable of disrupting the lipid bilayer structure. These data strongly suggest that the juxtamembrane motif of VAMP2 promotes SNARE-Munc18-1-mediated membrane fusion by destabilizing the membrane bilayer......
Document: Thus, the juxtamembrane motif of VAMP2 is intrinsically capable of disrupting the lipid bilayer structure. These data strongly suggest that the juxtamembrane motif of VAMP2 promotes SNARE-Munc18-1-mediated membrane fusion by destabilizing the membrane bilayer.
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