Author: Chew, Miaw-Fang; Poh, Keat-Seong; Poh, Chit-Laa
Title: Peptides as Therapeutic Agents for Dengue Virus Document date: 2017_10_15
ID: u1opdwmd_44
Snippet: The development of peptides as therapeutic drugs against viruses is a promising field for drug discovery. Peptides are known to be highly specific and selective against targets, have lower toxicity and low accumulation in tissues, all of which make them good candidates for drug development [193] . This phenomenon is in contrast to small molecule drugs, whereby off-target and toxicity are some of the biggest drawbacks for small molecule drugs [194.....
Document: The development of peptides as therapeutic drugs against viruses is a promising field for drug discovery. Peptides are known to be highly specific and selective against targets, have lower toxicity and low accumulation in tissues, all of which make them good candidates for drug development [193] . This phenomenon is in contrast to small molecule drugs, whereby off-target and toxicity are some of the biggest drawbacks for small molecule drugs [194, 195] . Although peptides possess several limitations, these could be overcome via chemical modifications.
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