Author: Reeder, Jens; Steffen, Peter; Giegerich, Robert
Title: pknotsRG: RNA pseudoknot folding including near-optimal structures and sliding windows Document date: 2007_5_3
ID: zgv4kd6j_18
Snippet: Recently, an unusual three-stemmed pseudoknot has been identified that promotes programmed -1 ribosomal frameshifting in the SARS Coronavirus (13) . The pseudoknot is thought to pause the ribosome during translation, which then shifts back by one nucleotide on the 'slippery site'. This special pseudoknot seems to be conserved in all Coronaviruses, and thus could be a target for anti-viral therapeutics......
Document: Recently, an unusual three-stemmed pseudoknot has been identified that promotes programmed -1 ribosomal frameshifting in the SARS Coronavirus (13) . The pseudoknot is thought to pause the ribosome during translation, which then shifts back by one nucleotide on the 'slippery site'. This special pseudoknot seems to be conserved in all Coronaviruses, and thus could be a target for anti-viral therapeutics.
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