Author: Gallily, Ruth; Warwick, Anne; Bang, Frederik B.
Title: ONTOGENY OF MACROPHAGE RESISTANCE TO MOUSE HEPATITIS IN VIVO AND IN VITRO Document date: 1967_3_31
ID: ub5l8hfu_14
Snippet: Delayed susceptibility in tissue culture was found to mirror the delayed susceptibility of the infant mice, but to be subject to modification by the environment. A difference in the culture media in the original study where 30 % serum was used, as contrasted to the 90 % serum used in the present study, may also partly explain the results, and should be investigated. It is suggested, then, that macrophages may be separated into three classes; (a) .....
Document: Delayed susceptibility in tissue culture was found to mirror the delayed susceptibility of the infant mice, but to be subject to modification by the environment. A difference in the culture media in the original study where 30 % serum was used, as contrasted to the 90 % serum used in the present study, may also partly explain the results, and should be investigated. It is suggested, then, that macrophages may be separated into three classes; (a) the mature genetically resistant, (b) the susceptible, and, (c) a delayed susceptible when derived from infant-resistant mice.
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