Selected article for: "Îg ml and IFN Î production"
Author: LI, Xunliang; LI, Pengchong; CAO, Liyan; BAI, Yunyun; CHEN, Huijie; LIU, He; REN, Xiaofeng; LI, Guangxing
Title: Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model
  • Document date: 2019_9_2
    • ID: rme6b022_35
    Snippet: IFN-γ and IL-4 levels in different sera were analyzed with ELISA. As shown in Table 1 , IFN-γ production was 1,222.32 ± 129.37 pg/ml for pVAX1-(TGEV-S1) group, while IL-4 level was 956.84 ± 122.06 pg/ml for pVAX1-(TGEV-S1) plus pVAX1-(pIL-12) group, which were significantly different from those reported for the control group (P<0.01). The concentration of IL-4 in pVAX1-(TGEV-S1) immunized groups was higher than that in other groups except pVA.....
    Document: IFN-γ and IL-4 levels in different sera were analyzed with ELISA. As shown in Table 1 , IFN-γ production was 1,222.32 ± 129.37 pg/ml for pVAX1-(TGEV-S1) group, while IL-4 level was 956.84 ± 122.06 pg/ml for pVAX1-(TGEV-S1) plus pVAX1-(pIL-12) group, which were significantly different from those reported for the control group (P<0.01). The concentration of IL-4 in pVAX1-(TGEV-S1) immunized groups was higher than that in other groups except pVAX1-(TGEV-S1) plus pVAX1-(pIL-12) group. The inactivated vaccine failed to induce IFN-γ and IL-4 production.

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