Author: Chun, Sejong; Chung, Chi Ryang; Ha, Young Eun; Han, Tae Hee; Ki, Chang-Seok; Kang, Eun-Suk; Park, Jin Kyeong; Peck, Kyong Ran; Cho, Duck
Title: Possible Transfusion-Related Acute Lung Injury Following Convalescent Plasma Transfusion in a Patient With Middle East Respiratory Syndrome Document date: 2016_4_25
ID: tawmg6g6_1
Snippet: Dear Editor, Korea suffered from an outbreak of the Middle East Respiratory Syndrome coronavirus (MERS-CoV) in May 2015 [1] . This endemic was the largest to have occurred outside of Saudi Arabia. Currently, a curative treatment for MERS is unavailable. Passive immunotherapy using convalescent plasma from recovering patients is suggested for positive clinical effects [2, 3] . However, the use of human plasma has potential risks including anaphyla.....
Document: Dear Editor, Korea suffered from an outbreak of the Middle East Respiratory Syndrome coronavirus (MERS-CoV) in May 2015 [1] . This endemic was the largest to have occurred outside of Saudi Arabia. Currently, a curative treatment for MERS is unavailable. Passive immunotherapy using convalescent plasma from recovering patients is suggested for positive clinical effects [2, 3] . However, the use of human plasma has potential risks including anaphylactic shock, transfusion-associated circulatory overload (TACO), and transfusion-related acute lung injury (TRALI) [4] . We describe our experience with administering a convalescent plasma infusion to a MERS patient that resulted in possible TRALI, which might have further accelerated the pulmonary manifestation of MERS in the patient.
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