Author: Dejnirattisai, Wanwisa; Webb, Andrew I.; Chan, Vera; Jumnainsong, Amonrat; Davidson, Andrew; Mongkolsapaya, Juthathip; Screaton, Gavin
Title: Lectin Switching During Dengue Virus Infection Document date: 2011_6_15
ID: qos9vu3r_41
Snippet: The difference in the binding specificities of dengue viruses produced in Vero versus primary dendritic cells was somewhat surprising and likely related to the expression of high-mannose moieties in Vero. A number of tumor cell lines express high-mannose sugars, and we have previously described the generation of a monoclonal antibody that recognizes a variety of tumor cell types and which binds to high-mannose moieties [38] . The differential aff.....
Document: The difference in the binding specificities of dengue viruses produced in Vero versus primary dendritic cells was somewhat surprising and likely related to the expression of high-mannose moieties in Vero. A number of tumor cell lines express high-mannose sugars, and we have previously described the generation of a monoclonal antibody that recognizes a variety of tumor cell types and which binds to high-mannose moieties [38] . The differential affinity of DC-SIGN for ligands expressed by tumor cell lines versus primary cells has been observed before and led some to speculate that DC-SIGN may participate in tumor surveillance [39] . There appears to be a further added level of complexity as the glycosylation profiles may vary in a given cell line depending on the exact position of the N-linked site within the polypeptide chain [29] .
Search related documents:
Co phrase search for related documents- bind specificity and dengue virus: 1
- bind specificity and monoclonal antibody: 1
- cell line and dendritic cell: 1, 2, 3, 4, 5
- cell line and dengue virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell line and exact position: 1
- cell line and high mannose: 1, 2, 3, 4, 5
- cell line and monoclonal antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell line and polypeptide chain: 1
- cell type and dendritic cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell type and dengue virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- cell type and high mannose: 1, 2, 3, 4, 5, 6
- cell type and monoclonal antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- dendritic cell and dengue virus: 1, 2, 3, 4, 5, 6, 7, 8
- dendritic cell and high mannose: 1, 2, 3, 4, 5, 6
- dendritic cell and monoclonal antibody: 1, 2
- dengue virus and high mannose: 1, 2, 3, 4
- dengue virus and monoclonal antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9
- glycosylation profile and high mannose: 1, 2
- high mannose and monoclonal antibody: 1, 2, 3, 4, 5, 6
Co phrase search for related documents, hyperlinks ordered by date