Author: Engering, Anneke; Hogerwerf, Lenny; Slingenbergh, Jan
                    Title: Pathogen–host–environment interplay and disease emergence  Document date: 2013_2_6
                    ID: t2pgb4l9_20
                    
                    Snippet: The process of a pathogen that emerges in a novel host has been well described by Wolfe et al. 10 , subsequently adapted by others. 8, 9 In summary, different stages can be discerned starting from a pathogen that only infects reservoir hosts, to spill-over without subsequent transmission in the novel host (with R 0 in novel host50, where R 0 is the expected number of secondary cases per primary case 29 ), stuttering chains of infection (R 0 ,1 30.....
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: The process of a pathogen that emerges in a novel host has been well described by Wolfe et al. 10 , subsequently adapted by others. 8, 9 In summary, different stages can be discerned starting from a pathogen that only infects reservoir hosts, to spill-over without subsequent transmission in the novel host (with R 0 in novel host50, where R 0 is the expected number of secondary cases per primary case 29 ), stuttering chains of infection (R 0 ,1 30 ), and finally sustained novel host-to-novel host transmission (R 0 .1).
 
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