Selected article for: "dna vaccine and IBV vaccine"
Author: Yan, Fang; Zhao, Yujun; Hu, Yongting; Qiu, Jianyang; Lei, Wenxin; Ji, Wenhui; Li, Xuying; Wu, Qian; Shi, Xiumin; Li, Zhong
Title: Protection of chickens against infectious bronchitis virus with a multivalent DNA vaccine and boosting with an inactivated vaccine
  • Document date: 2013_3_24
    • ID: wwuqxx1r_28
    Snippet: Our results directly demonstrated that the multivalent DNA vaccine targeting the S1, M, and N proteins of IBV developed humoral and cellular immune responses against IBV in chickens. We also showed that our prime-boost immunization strategy induced strong immune responses and provided effective protection from challenge with a high dose of virulent IBV. DNA vaccines are easy to prepare and inactivated vaccines are readily available. Administratio.....
    Document: Our results directly demonstrated that the multivalent DNA vaccine targeting the S1, M, and N proteins of IBV developed humoral and cellular immune responses against IBV in chickens. We also showed that our prime-boost immunization strategy induced strong immune responses and provided effective protection from challenge with a high dose of virulent IBV. DNA vaccines are easy to prepare and inactivated vaccines are readily available. Administration of DNA vaccines with an inactivated vaccine is a safe and effective immunization technique. Given its superior efficacy, this combination represents a valuable strategy for protecting against IBV infection and can combat poor cross-protection among the numerous IBV serotypes along with the frequent emergence of new variants.

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